Protheragen Focuses on Eye Health
Due to demographic changes and an aging population, the number of people with visual impairment (VI) and blindness is increasing in the United States and globally. We are facing the challenge of increasing incidence of age- and lifestyle-related degenerative eye diseases, including cataracts, glaucoma, age-related macular degeneration (AMD), dry eye and diabetic retinopathy. Additionally, people who are visually impaired or blind are at higher risk for chronic health conditions such as unintentional injuries, social withdrawal, depression, etc.
Therefore, an important goal of Protheragen is to improve vision health through interventions and increasing consumer awareness of preventive health care. We still need to remind you that nutritional supplements for eye health should only be used as an adjunct to prevention and eye protection, but not as a complete replacement for medication.
Nutraceuticals for Eye Health
Lutein/Zeaxanthin
Lutein and zeaxanthin are carotenoids that accumulate in the retina, do not have vitamin A activity, but are concentrated in the macula, which can resist photo-oxidation. Numerous studies have demonstrated the protective effects of lutein, zeaxanthin and beta-carotene against eye diseases and macular degeneration. [1]
Anthocyanin
Anthocyanins have antioxidant and anti-inflammatory properties that can reverse oxidative stress and may improve certain diseases. Studies have indicated that anthocyanins can protect the retina from overexposure to visible light and exposure to radiation, as well as improve vision and increase blood supply to the retina.
Omega-3 fatty acids (EPA, DHA)
More than half of the retinal photoreceptor cell membrane is DHA, which helps the retina and optic nerve face oxidative stress, avoids apoptosis, and protects retinal nerve cells. In addition, it can replenish the lipid layer in tears, making tears less volatile and preventing dry eyes. EPA can reduce inflammation such as redness and itching caused by dry eyes. [2, 3]
Vitamins
Studies on vitamin supplementation to prevent or reduce eye disease have reported controversial results, so here are some representative studies for your reference.[1]
Mineral
Zinc is found in the tissues of the eye, especially the retina. Supplementing zinc in moderation can help protect the retina. A randomized, prospective, placebo-controlled clinical trial showed that zinc monocysteine (ZMC) supplementation significantly improved visual acuity and contrast sensitivity and significantly shortened the time to recovery from macular flashes at three and six months. [4]
References- Hock Eng Khoo. (2019). "Nutrients for Prevention of Macular Degeneration and Eye-Related Diseases," Antioxidants 8(4), 85.
- Rahul Bhargava. (2013). "A randomized controlled trial of omega-3 fatty acids in dry eye syndrome," Int J Ophthalmol 6(6), 811-6.
- Jordi Gatell-Tortajada. (2016). "Oral supplementation with a nutraceutical formulation containing omega-3 fatty acids, vitamins, minerals, and antioxidants in a large series of patients with dry eye symptoms: results of a prospective study," Clin Interv Aging 11, 571–578.
- David A. Newsome. (2008). "A Randomized, Prospective, Placebo-Controlled Clinical Trial of a Novel Zinc-Monocysteine Compound in Age-Related Macular Degeneration," Current Eye Research 33(7), 591-598.
※ These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure or prevent any
disease.
