Protheragen Focuses on Digestive Health
The health of the digestive system is important for it to perform its physiological functions properly. The gastrointestinal (GI) tract is a complex ecosystem exposed to many food components and bacteria. The gut barrier is key to gut health by protecting the body from bacteria and toxins. Any disruption of the gut barrier can lead to infectious, inflammatory and functional gastrointestinal disorders. The gut microbiota affects the state of the immune system, regulates energy metabolism, and even affects brain function and behavior.
In recent years, alternatives, functional foods, safer bioactive compounds, or nutraceutical-based approaches to gastrointestinal disease management have been increasingly considered. Many nutraceuticals with antioxidative, anti-inflammatory, fatty acid, probiotic, and prebiotic properties have been found to improve signs of gastrointestinal disease.
Nutraceuticals provided by Protheragen can be used as an auxiliary protection and treatment for digestive health and gastrointestinal diseases, but cannot completely replace medicines.
Nutraceuticals for Digestive Health
Polyphenols
Polyphenols are a variety of antioxidant, anti-inflammatory, antibacterial and anticancer compounds derived from various plant sources such as tea, wine, olives, grapes, cocoa and turmeric, of which catechins, curcumin and anthocyanins are the main components to protect the stomach.
Polyunsaturated Fatty Acids (PUFAS)
Numerous studies point to the promise of omega-3 PUFAs as an adjunct therapy in the management of gastrointestinal disorders. The mechanism of action is by controlling inflammatory pathways, inhibiting cell-mediated responses, reducing NF-κB expression and improving intestinal barrier function. [1]
Probiotics, Prebiotics and Synbiotics
Ingestion of probiotics has minimal health risks and has beneficial effects by increasing host-friendly commensal bacteria and reducing evasive pathogenic organisms, which is particularly useful in patients with irritable bowel disease (IBD) and H. pylori infection. Prebiotics are oligosaccharides and polysaccharides that are indigestible by humans and serve as substrates for the growth of probiotics. Synbiotics refer to combinations of prebiotics and probiotics that promote beneficial gut microflora.
Phytosterols
Phytosterols have anti-inflammatory properties in addition to their cholesterol-lowering effects. Studies have shown the potential of phytosterols in the management of inflammatory gastrointestinal diseases. Phytosterol pretreatment alleviates clinical symptoms and exerts a protective effect on dextran sulfate sodium (DSS)-induced colonic inflammation, reduces the infiltration of inflammatory cells and accelerates mucosal healing. [2]
Fat-Soluble Vitamins
Among the fat-soluble vitamins, A and D have been highlighted in the literature for addressing gastrointestinal disorders. By inhibiting or reducing colitis, vitamin A indirectly protects against colon cancer. Vitamin D deficiency is common in IBD patients and is associated with TNF-α-mediated inflammation. [1]
References- Natasha Yang. (2017). "Recent advances in complementary and replacement therapy with nutraceuticals in combating gastrointestinal illnesses," Clinical Nutrition 36(4), 968-979.
- Rita Aldini. (2014). "Antiinflammatory Effect of Phytosterols in Experimental Murine Colitis Model: Prevention, Induction, Remission Study," PLoS ONE 9(9): e108112.
※ These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure or prevent any
disease.
