Creatine is a nitrogen-containing organic acid that occurs naturally in animals. 95% of the creatine in the human body is in skeletal muscle, and the remaining 5% is in the brain, liver, kidneys and testes. Protheragen Nutraceuticals provides you with a high-quality creatine supplement commonly used by strength athletes.
The Action Mechanism of Creatine
High-energy cells require the use of creatine in the form of phosphocreatine. After creatine supplementation, it can be converted into creatine phosphate by phosphorylation. Creatine phosphate is a source of phosphate that produces adenosine triphosphate (ATP) from adenosine diphosphate (ADP). Studies have shown that when skeletal muscle cells store sufficient ATP and creatine phosphate for approximately 10 seconds of high-intensity activity; short-term creatine supplementation results in a 10 to 30 percent increase in total creatine and 10 to 30 percent in creatine phosphate reserves 40%. [1]
The Sports Benefits of Creatine
Creatine is one of the most researched and popular enhancers for athletes and recreational weightlifters, designed to improve athletic and athletic performance, enhance athletic training adaptation, and reduce recovery time.
Helps improve muscle strength
Research has shown that the mean increase in muscle strength after creatine supplementation plus resistance training is 8% higher than the mean increase in muscle strength after placebo intake during resistance training. Similarly, the mean increase in weightlifting performance after creatine supplementation plus resistance training. [2]
Help improve athletic performance
A review summarizes the available information on the efficacy of creatine supplementation on exercise and athletic performance, noting that creatine supplementation has the potential benefits described in the table below. In conclusion, creatine supplementation has positive effects on strength and power, sport-specific performance, exercise capacity/prolonged high-intensity efforts, and endurance performance. [3]
Improving fat-free mass
Creatine monohydrate (CrM) increases fat-free mass and muscle power output. Antonio et al. observed improvements in fat-free mass accumulation and bench press 1 RM intensity in recreational male bodybuilders after a 5-week creatine supplementation period in combination with a bodybuilding-type resistance training program. [4]
Improving sports-induced injuries
Creatine intake is an effective strategy to improve recovery from exercise-induced injury, muscle damage, and oxidative stress. [5]
Precautions
- Not recommended in combination with any medications that affect the kidneys.
- Creatine affects water levels in the body, so drink enough water to prevent dehydration.
- It should be avoided by children under 18 and women who are pregnant or breastfeeding.
- Creatine may also affect blood sugar levels.
- Please consult your doctor before taking creatine or any other supplement.
Related Research Information
The effect of creatine on the treatment of depression
There is an association between treatment-resistant depression and decreased brain creatine phosphocreatine concentrations. Creatine therapy may be a promising treatment for women with depression and co-methamphetamine dependence, a study suggests. [6]
Effects of creatine on nervous system diseases
Creatine is not only good for muscles, but also for the brain. Patients with creatine deficiency syndrome present with mental retardation, delayed speech and language, and epilepsy. Studies have found that creatine can help improve brain function, such as helping to improve cognitive function and reduce mental fatigue. [7]
References- Jessica Butts. (2017). "Creatine Use in Sports,"Sports Health 10(1), 31-34.
- Eric S Rawson. (2003). "Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance," J Strength Cond Res. 17(4), 822-31.
- Benjamin Wax. (2021). "Creatine for Exercise and Sports Performance, with Recovery Considerations for Healthy Populations," Nutrients. 13(6), 1915.
- Jose Antonio. (2013). "The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength," Journal of the International Society of Sports Nutrition 10, 36.
- Robert Cooper. (2012). "Creatine supplementation with specific view to exercise/sports performance: an update," J Int Soc Sports Nutr. 9, 33.
- Tracy L. Hellem. (2015). "Creatine as a Novel Treatment for Depression in Females Using Methamphetamine: A Pilot Study," Journal of Dual Diagnosis 11(3-4), 189-202.
- Caroline Rae. (2003). "Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial," Proc Biol Sci. 270(1529), 2147–2150.
※ These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure or prevent any
disease.
